Diphenhydramine HCl Diphenhydramine hydrochloride 25 mg
Generic for: Acetadryl, Aleve PM, Banophen, Banophen Cream, Benadryl, Benadryl Allergy Plus Congestion, Benadryl Itch Stopping, Benadryl-D Allergy and Sinus, Buckley's Bedtime Formula, Calagel, Calagel Reformulated Jun 2019, Compoz, Dermamycin, Diphedryl, Diphenhist, Doans PM, Dormin, Genahist, Ivarest, Ivarest Maximum Strength, Kids-Eeze Allergy, Legatrin PM, Nytol, Panadol PM, Pediaclear Cough, Percogesic Reformulated Jan 2011, Rest Simply, Scot-Tussin Allergy, Siladryl, Simply Sleep, Sleep-Eze, Sleepinal, Sominex, Somnapure, Tact, Tekral, The Itch Eraser, Twilite, Tylenol PM, Unisom Sleep, Unisom with Pain Relief, Vanamine, Vetadryl, Wal-Dryl, Wal-Dryl Allergy, Wal-Dryl Childrens, Wal-Dryl PE, Wal-Dryl-D, Wal-Sleep Z, Wal-Som, Wal-Som Maximum Strength, Z-Sleep, ZZZ Sleep, Zzzquil
💰 Pharmacy Cost Benchmark
$0.06 / tablet
30-day estimate: $1.81 · 90-day: $5.43
Source: NADAC (CMS) · Effective: 2026-05-20
Pricing shown is for a therapeutically equivalent product (same active ingredient, strength, and dose form). Equivalent NDC: 70000-0598-02
Pricing resolved from a therapeutically equivalent NDC via RxCUI because the exact package lacked a current NADAC row.
Estimated fair retail range
$2.72 – $5.44
For a typical 30-day supply (1 unit/day).
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📈 Price History (last 12 months)
▼ -4.4% since Dec 2025
⚠️ Important
- NADAC reflects pharmacy acquisition cost, not your out-of-pocket cost.
- Actual prices vary by pharmacy, insurance, and location.
- This is not medical advice. Always consult your pharmacist.