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Medication Guide — DOXYCYCLINE HYCLATE

Patient-friendly FDA guidance and safety information.

Last updated · May 13, 2026Source: DailyMed ↗

Poison Help

If you suspect an overdose or accidental ingestion, call Poison Control: 1-800-222-1222 (free, 24/7, U.S.). For life-threatening symptoms, call 911.

FDA-Approved PATIENT LABELING

Doxycycline hyclate delayed-release tablets, USP, 50 mg, 150 mg and 200 mg

Instructions for Breaking the 150 mg Doxycycline Hyclate Delayed-Release Dual-Scored Tablet

Your doctor may find it necessary to adjust your dosage of doxycycline hyclate delayed-release tablets to obtain the proper treatment response. The tablet is marked with separation lines (score lines) and may be broken at these score lines to provide any of the following doses.

If your doctor prescribed:

  • 150 mg treatment (take the entire table)
  • 100 mg treatment (take two thirds of the tablet or two 50 mg tablet segments)
  • 50 mg treatment (take one third of the tablet)

To break the tablet, hold the tablet between your thumbs and index fingers close to the appropriate score line. Then, with the score line facing you, apply enough pressure to snap the tablet segments apart (do not use segments that do not break along the score line).

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Sources

RxCUI: 799048

NDC: 43547-324

Last fetched: May 13, 2026

Source: DailyMed ↗

⚠️ Disclaimer

This information is for educational purposes only and is not medical advice. Always consult your doctor, pharmacist, or other licensed healthcare professional before starting, stopping, or changing any medicine. Read full medical disclaimer.

DOXYCYCLINE HYCLATE Medication Guide, Warnings & FDA Label | PillSeek