Innopran Medication Summary
No separate FDA Medication Guide was found for this label. This summary is based on FDA/DailyMed prescribing information.
What is this medication?
This medication is described in FDA/DailyMed prescribing information. No separate FDA Medication Guide was found for this label. This summary is based on FDA/DailyMed prescribing information.
What is this medication used for?
INNOPRAN XL is indicated for the treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes, including beta-blockers. Control of high blood pressure should be part of comprehensive cardiovascular risk management, including, as appropriate, lipid control, diabetes management, antithrombotic therapy, smoking cessation, exercise, and limited sodium intake. Many patients will require more than one drug to achieve blood pressure goals. For specific.
What should I know before taking it?
INNOPRAN XL is contraindicated in patients with: •Cardiogenic shock or decompensated heart failure •Sinus bradycardia, sick sinus syndrome, and greater than first-degree block unless a permanent pacemaker is in place •Bronchial asthma •Known hypersensitivity (e.g., anaphylactic reaction) to propranolol hydrochloride or any of the components of INNOPRAN XL
What important warnings are listed?
Abrupt cessation may exacerbate myocardial ischemia. (5.1) May worsen congestive heart failure. (5.2) Avoid discontinuing therapy prior to major surgery. (5.3) Diabetes: May mask symptoms of hypoglycemia, and alter glucose levels; monitor. (5.4) Bradycardia. (5.6)
How is this medication usually taken?
INNOPRAN XL should be administered once daily at bedtime and should be taken consistently either on an empty stomach or with food. Initiate dosing at 80 mg and titrate to 120 mg daily as needed for blood pressure control. Doses above 120 mg have no additional effects on blood pressure [see Clinical Studies (14.1)]. Full antihypertensive response is usually achieved within 2 to 3 weeks. INNOPRAN XL Extended Release Capsules are supplied as capsules containing either 80 mg (equivalent to 70.14 mg of propranolol) or 120 mg (equivalent to 105.21 mg of propranolol) of propranolol hydrochloride imprinted with “InnoPran XL”. In addition, the 80 mg strength is a gray/white capsule imprinted with.
What side effects are listed?
The most commonly reported adverse reactions (≥3% and greater than placebo) included the following: fatigue, dizziness, and constipation. (6.1) To report SUSPECTED ADVERSE REACTIONS, contact ANI Pharmaceuticals, Inc. at 1-800-308-6755 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
What interactions are listed?
CYP2D6, 1A2, or 2C19 enzyme inhibitors increase propranolol levels. (7.1) CYP1A2 and 2C19 inducers decrease propranolol levels. (7.1) Monitor prothrombin time when propranolol is co-administered with warfarin. (7.1)
Where can I find the official prescribing information?
Review the full prescribing information on DailyMed: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=cd5601b3-4d87-4c3b-acac-b476e787609d
⚠️ Disclaimer
This summary is for educational purposes only and is not medical advice. Always consult your doctor, pharmacist, or other licensed healthcare professional before starting, stopping, or changing any medicine. Read full medical disclaimer.