Lomotil Medication Summary
No separate FDA Medication Guide was found for this label. This summary is based on FDA/DailyMed prescribing information.
What is this medication?
This medication is described in FDA/DailyMed prescribing information. No separate FDA Medication Guide was found for this label. This summary is based on FDA/DailyMed prescribing information.
What is this medication used for?
Lomotil is indicated as adjunctive therapy in the management of diarrhea in patients 13 years of age and older.
What should I know before taking it?
Lomotil is contraindicated in: •Pediatric patients less than 6 years of age due to the risks of respiratory and central nervous system (CNS) depression (see WARNINGS ). •Patients with diarrhea associated with pseudomembranous enterocolitis (Clostridium difficile) or other enterotoxin-producing bacteria due to the risk of gastrointestinal (GI) complications, including sepsis (see WARNINGS ). •Patients with known hypersensitivity to diphenoxylate or atropine. •Patients with obstructive jaundice.
What important warnings are listed?
The FDA/DailyMed label should be reviewed for complete details.
How is this medication usually taken?
Advise patients: •Accidental ingestion of Lomotil in children, especially in those less than 6 years of age, may result in severe respiratory depression or coma. Instruct patients to take steps to store Lomotil securely and out of reach of children, and to dispose of unused Lomotil (see WARNINGS ). •To take Lomotil at the prescribed dosage. Use of a higher than prescribed dosage may include opioid and/or anticholinergic effects (see OVERDOSAGE ). Report to a healthcare facility if they develop anticholinergic symptoms such as hyperthermia, flushing, tachycardia, tachypnea, hypotonia, lethargy, hallucinations, febrile convulsion, dry mouth, mydriasis or opioid symptoms such as progressive.
What side effects are listed?
The following serious adverse reactions are described elsewhere in labeling: •Respiratory and/or CNS depression (see WARNINGS ) •Anticholinergic and opioid-toxicities, including atroponism (see WARNINGS and PRECAUTIONS ) •Dehydration and electrolyte imbalance (see WARNINGS ) •GI Complications in patients with infectious diarrhea (see WARNINGS ) •Toxic megacolon in patients with acute ulcerative colitis (see WARNINGS ) At therapeutic doses of Lomotil, the following other adverse reactions have been reported; they are listed in decreasing order of severity, but not of frequency: Nervous system: numbness of extremities, euphoria, depression, malaise/lethargy, confusion, sedation/drowsiness,.
What interactions are listed?
The FDA/DailyMed label should be reviewed for complete details.
Where can I find the official prescribing information?
Review the full prescribing information on DailyMed: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f170584a-1072-4fd7-b1dc-6756703483b9
⚠️ Disclaimer
This summary is for educational purposes only and is not medical advice. Always consult your doctor, pharmacist, or other licensed healthcare professional before starting, stopping, or changing any medicine. Read full medical disclaimer.