Metformin hydrochloride Metformin hydrochloride 500 mg

Generic for: Actoplus Met, Glucophage, Glumetza, Invokamet, Janumet, Jentadueto, Kazano, Kombiglyze, Riomet, Segluromet, Synjardy, Trijardy, Xigduo, Zituvimet

💰 Pharmacy Cost Benchmark

$5.28 / tablet

30-day estimate: $158.31 · 90-day: $474.93

Source: NADAC (CMS) · Effective: 2025-12-17

Pricing shown is an estimate based on the active ingredient. The exact strength, dose form, and packaging may differ.

Pricing estimated from an ingredient/name-based match because no exact or sibling-family NADAC row was available.

Basis: Ingredient-level name match for metformin

Estimated fair retail range

$237.47 – $474.93

For a typical 30-day supply (1 unit/day).

🔄 Compare Alternatives

Drug	Per-unit cost	30-day supply
brand — metformin hydrochloride 1000 MG / sitagliptin 50 MG Oral Tablet [Zituvimet]← cheapest	$5.03 / EA	$150.94
brand — 24 HR metformin hydrochloride 1000 MG / sitagliptin phosphate 50 MG Extended Release Oral Tablet [Janumet]	$5.28 / EA	$158.29
brand — 24 HR metformin hydrochloride 500 MG / sitagliptin phosphate 50 MG Extended Release Oral Tablet [Janumet]	$5.28 / EA	$158.47
brand — sitagliptin 50 MG Oral Tablet [Zituvio]	$10.04 / EA	$301.10
brand — sitagliptin 25 MG Oral Tablet [Zituvio]	$10.05 / EA	$301.45

📈 Price History (last 12 months)

▲ +25.3% since Aug 2013

⚠️ Important

NADAC reflects pharmacy acquisition cost, not your out-of-pocket cost.
Actual prices vary by pharmacy, insurance, and location.
This is not medical advice. Always consult your pharmacist.