METOPROLOL SUCCINATE Medication Summary
No separate FDA Medication Guide was found for this label. This summary is based on FDA/DailyMed prescribing information.
What is this medication?
METOPROLOL SUCCINATE is described in FDA/DailyMed prescribing information. No separate FDA Medication Guide was found for this label. This summary is based on FDA/DailyMed prescribing information.
What is this medication used for?
1 INDICATIONS AND USAGE Metoprolol succinate extended-release tablets, are a beta-adrenergic blocker indicated for the treatment of: • Hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and non-fatal cardiovascular events, primarily strokes and myocardial infarctions. ( 1.1 ) • Angina Pectoris. ( 1.2 ) • Heart Failure, to reduce the risk of cardiovascular mortality and heartfailure hospitalizations in patients with heart failure ( 1.3 ) 1.1 Hypertension Metoprolol succinate extended-release tablets are indicated for the treatment of hypertension, to lower blood pressure. Lowering blood pressure lowers the risk of fatal and non-fatal cardiovascular.
What should I know before taking it?
Metoprolol succinate extended-release tablets are contraindicated in severe bradycardia, second or third degree heart block, cardiogenic shock, decompensated heart failure, sick sinus syndrome (unless a permanent pacemaker is in place), and in patients who are hypersensitive to any component of this product.
What important warnings are listed?
5 WARNINGS AND PRECAUTIONS • abrupt cessation may exacerbate myocardial ischemia. ( 5.1 ) • Heart Failure: Worsening cardiac failure may occur. ( 5.2 ) • Bronchospastic Disease: Avoid beta blockers. ( 5.3 ) • Concomitant use of glycosides, clonidine, and diltiazem and verapamil with beta-blockers can increase the risk of bradycardia. ( 5.4 ) • PheochromocytomaInitiate therapy with an alpha blocker. ( 5.5 ) • Major Surgery: Avoid initiation of high-dose extended-release metoprolol in patients undergoing non-cardiac surgery. Do not routinely withdraw chronic beta blocker therapy prior to surgery. ( 5. 6 , 6.1 ) • Diabetes and Hypoglycemia: May mask tachycardia occurring with hypoglycemia. (.
How is this medication usually taken?
25 mg tablets: White to off white, oval, biconvex film coated tablets score line on both sides debossed with 'J' on one side and '75' on the other side separating 7 & 5 with score line. 50 mg tablets: White to off white, round, biconvex film coated tablets debossed with 'J' on one side and '76' on the other side separating 7 & 6 with score line. 100 mg tablets: White to off white, round, biconvex film coated tablets debossed with 'J' on one side and '77' on the other side separating 7 & 7 with score line. 200 mg tablets: White to off white, oval, biconvex film coated tablets debossed with 'J' on one side and '78' on the other side separating 7 & 8 with score line.
What side effects are listed?
The following adverse reactions are described elsewhere in labeling: •Worsening angina or myocardial infarction. [see Warnings and Precautions (5)] •Worsening heart failure. [see Warnings and Precautions (5)] •Worsening AV block. [see Contraindications (4)]
What interactions are listed?
7 DRUG INTERACTIONS • Catecholamine-depleting drugs may have an additive effect when given with beta-blocking agents. ( 7.1 ) • CYP2D6 Inhibitors are likely to increase metoprolol concentration. ( 7.2 ) • Beta-blockers including metoprolol, may exacerbate the rebound hypertension that can follow the withdrawal of clonidine. ( 7.3 ) 7.1 Catecholamine Depleting Drugs Catecholamine depleting drugs (eg., reserpine, monoamine oxidase (MAO) inhibitors) may have an additive effect when given with beta-blocking agents. Observe patients treated with metoprolol succinate extended-release tablets plus a catecholamine depletor for evidence of hypotension or marked bradycardia, which may produce.
Where can I find the official prescribing information?
Review the full prescribing information on DailyMed: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=09fa1b7f-1911-4bc2-825b-c885a44f5c63
⚠️ Disclaimer
This summary is for educational purposes only and is not medical advice. Always consult your doctor, pharmacist, or other licensed healthcare professional before starting, stopping, or changing any medicine. Read full medical disclaimer.