Phentermine Hydrochloride E 882 E 882 00185 0644 01 Medication Summary
No separate FDA Medication Guide was found for this label. This summary is based on FDA/DailyMed prescribing information.
What is this medication?
This medication is described in FDA/DailyMed prescribing information. No separate FDA Medication Guide was found for this label. This summary is based on FDA/DailyMed prescribing information.
What is this medication used for?
Phentermine hydrochloride capsules are indicated as a short-term (a few weeks) adjunct in a regimen of weight reduction based on exercise, behavioral modification and caloric restriction in the management of exogenous obesity for patients with an initial body mass index ≥30 kg/m2, or ≥27 kg/m2 in the presence of other risk factors (e.g., controlled hypertension, diabetes, hyperlipidemia). Below is a chart of body mass index (BMI) based on various heights and weights. BMI is calculated by taking the patient's weight, in kilograms (kg), divided by the patient's height, in meters (m), squared. Metric conversions are as follows: pounds ÷ 2.2 = kg; inches × 0.0254 = meters. Height (feet, inches).
What should I know before taking it?
History of cardiovascular disease (e.g., coronary artery disease, stroke, arrhythmias, congestive heart failure, uncontrolled hypertension)During or within 14 days following the administration of monoamine oxidase inhibitorsHyperthyroidismGlaucomaAgitated statesHistory of drug abusePregnancy [see Use in Specific Populations (8.1) ]Nursing [see Use in Specific Populations (8.3) ]Known hypersensitivity, or idiosyncrasy to the sympathomimetic amines
What important warnings are listed?
Coadministration with other drugs for weight loss is not recommended (safety and efficacy of combination not established). (5.1)Rare cases of primary pulmonary hypertension have been reported. Phentermine should be discontinued in case of new, unexplained symptoms of dyspnea, angina pectoris, syncope or lower extremity edema. (5.2)Rare cases of serious regurgitant cardiac valvular disease have been reported. (5.3)Tolerance to the anorectic effect usually develops within a few weeks. If this occurs, phentermine should be discontinued. The recommended dose should not be exceeded. (5.4)Phentermine may impair the ability of the patient to engage in potentially hazardous activities such as.
How is this medication usually taken?
Capsules containing 15 mg or 30 mg phentermine hydrochloride (equivalent to 12 mg or 24 mg phentermine base, respectively). 15 mg capsules: gray/yellow; imprinted "EL600" in black ink on cap and body, filled with white to off-white powder. 30 mg capsules: yellow; imprinted "EL601" in black ink on cap and body, filled with white to off-white powder.
What side effects are listed?
The following adverse reactions are described, or described in greater detail, in other sections: -Primary pulmonary hypertension [see Warnings and Precautions (5.2) ] -Valvular heart disease [see Warnings and Precautions (5.3) ] -Effect on the ability to engage in potentially hazardous tasks [see Warnings and Precautions (5.5) ] -Withdrawal effects following prolonged high dosage administration [see Drug Abuse and Dependence (9.3) ] The following adverse reactions to phentermine have been identified:
What interactions are listed?
Monoamine oxidase inhibitors: Risk of hypertensive crisis. (4, 7.1)Alcohol: Consider potential interaction (7.2)Insulin and oral hypoglycemics: Requirements may be altered. (7.3)Adrenergic neuron blocking drugs: Hypotensive effect may be decreased by phentermine. (7.4)
Where can I find the official prescribing information?
Review the full prescribing information on DailyMed: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=e48feec6-50c9-4ccd-b9da-56956d14c853
⚠️ Disclaimer
This summary is for educational purposes only and is not medical advice. Always consult your doctor, pharmacist, or other licensed healthcare professional before starting, stopping, or changing any medicine. Read full medical disclaimer.