Plaquenil Medication Summary
No separate FDA Medication Guide was found for this label. This summary is based on FDA/DailyMed prescribing information.
What is this medication?
This medication is described in FDA/DailyMed prescribing information. No separate FDA Medication Guide was found for this label. This summary is based on FDA/DailyMed prescribing information.
What is this medication used for?
PLAQUENIL is an antimalarial and antirheumatic indicated for the: • Treatment of uncomplicated malaria due to Plasmodium falciparum, Plasmodium malariae, Plasmodium ovale, and Plasmodium vivax in adult and pediatric patients. (1.1) • Prophylaxis of malaria in geographic areas where chloroquine resistance is not reported in adult and pediatric patients (1.1) • Treatment of rheumatoid arthritis in adults. (1.2) • Treatment of systemic lupus erythematosus in adults. (1.3) • Treatment of chronic discoid lupus erythematosus in adults. (1.4) Limitations of Use (1.1): PLAQUENIL is not recommended for the: • Treatment of complicated malaria. • Treatment of chloroquine or.
What should I know before taking it?
PLAQUENIL is contraindicated in patients with known hypersensitivity to 4-aminoquinoline compounds
What important warnings are listed?
Cardiomyopathy and Ventricular Arrhythmias: Fatal or life-threatening cardiomyopathy and ventricular arrhythmias were reported. (5.1) • Retinal Toxicity: Irreversible retinal damage is related to cumulative dosage and treatment duration. Baseline retinal exam and exams during treatment are recommended. (5.2) • Serious Skin Reactions: Stevens Johnson syndrome, toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms, acute generalized exanthematous pustulosis have been reported. (5.3) • Worsening of Psoriasis and Porphyria: Avoid in patients with psoriasis or porphyria. (5.4) • Hematologic Toxicity: Discontinue if myelosuppression occurs. (5.5) Renal.
How is this medication usually taken?
Tablets: 200 mg of hydroxychloroquine sulfate, white to off-white, film-coated tablet imprinted with “PLAQUENIL” on one face in black ink.
What side effects are listed?
The following adverse reactions are described in greater detail in other sections: • Cardiomyopathy and Ventricular Arrhythmias [see Warnings and Precautions (5.1)] • Retinal Toxicity [see Warnings and Precautions (5.2)] • Serious Skin Reactions [see Warnings and Precautions (5.3)] • Worsening of Psoriasis and Porphyria [see Warnings and Precautions (5.4)] • Hematologic Toxicity [see Warnings and Precautions (5.5)] • Hemolytic Anemia Associated with G6PD [see Warnings and Precautions (5.6)] • Skeletal Muscle Myopathy or Neuropathy [see Warnings and Precautions (5.7)] • Neuropsychiatric Reactions Including Suicidality [see Warnings and Precautions (5.8)] • Hypoglycemia [see Warnings and.
What interactions are listed?
Drugs Prolonging QT Interval and Other Arrhythmogenic Drugs. ( 7.1) • See FPI for more important drug interactions.( 7)
Where can I find the official prescribing information?
Review the full prescribing information on DailyMed: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=eb26c050-fc41-4183-9f8c-86351335fa64
⚠️ Disclaimer
This summary is for educational purposes only and is not medical advice. Always consult your doctor, pharmacist, or other licensed healthcare professional before starting, stopping, or changing any medicine. Read full medical disclaimer.