← Back to Promethazine hydrochloride

Promethazine hydrochloride 25 mg
NDC: 00591-5307-01
💰 Pharmacy Cost Benchmark
$0.05 / tablet
30-day estimate: $1.43 · 90-day: $4.29
Source: NADAC (CMS) · Effective: 2026-05-20
Estimated fair retail range
$2.14 – $4.29
For a typical 30-day supply (1 unit/day).
🔄 Compare Alternatives
| Drug | Per-unit cost | 30-day supply |
|---|---|---|
| generic — codeine phosphate 2 MG/ML / promethazine hydrochloride 1.25 MG/ML Oral Solution← cheapest | $0.05 / ML | $1.50 |
| brand — promethazine hydrochloride 12.5 MG Rectal Suppository [Promethegan] | $1.88 / EA | $56.41 |
| brand — promethazine hydrochloride 25 MG Rectal Suppository [Promethegan] | $1.93 / EA | $57.90 |
| brand — promethazine hydrochloride 50 MG Rectal Suppository [Promethegan] | $24.54 / EA | $736.30 |
📈 Price History (last 12 months)
▼ -51.1% since Nov 2013
⚠️ Important
- NADAC reflects pharmacy acquisition cost, not your out-of-pocket cost.
- Actual prices vary by pharmacy, insurance, and location.
- This is not medical advice. Always consult your pharmacist.