Ramipril Za 43 1 25 Mg 68382 0144 06 Medication Summary
No separate FDA Medication Guide was found for this label. This summary is based on FDA/DailyMed prescribing information.
What is this medication?
This medication is described in FDA/DailyMed prescribing information. No separate FDA Medication Guide was found for this label. This summary is based on FDA/DailyMed prescribing information.
What is this medication used for?
Ramipril capsules are an angiotensin converting enzyme (ACE) inhibitor indicated for the treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions. It may be used alone or in combination with thiazide diuretics ( 1.1). Ramipril capsules are indicated in stable patients who have demonstrated clinical signs of congestive heart failure post-myocardial infarction ( 1.3).
What should I know before taking it?
Ramipril capsules are contraindicated in patients who are hypersensitive to this product or any other ACE inhibitor (e.g., a patient who has experienced angioedema during therapy with any other ACE inhibitor). Ramipril capsules are contraindicated in combination with a neprilysin inhibitor (e.g., sacubitril). Do not administer ramipril capsules within 36 hours of switching to or from sacubitril/valsartan, a neprilysin inhibitor [see Warnings and Precautions ( 5.1 )]. Do not co-administer ramipril capsules with aliskiren: • in patients with diabetes
What important warnings are listed?
When pregnancy is detected, discontinue ramipril as soon as possible ( 5.6 ). Drugs that act directly on the renin-angiotensin system can cause injury and death to the developing fetus ( 5.6 ). WARNING: FETAL TOXICITY See full prescribing information for complete boxed warning
How is this medication usually taken?
Ramipril capsules are supplied as hard gelatin capsules containing 1.25 mg, 2.5 mg, 5 mg, and 10 mg of ramipril.
What side effects are listed?
The most common adverse reactions in patients with hypertension included headache, dizziness, fatigue, and cough ( 6.1). To report SUSPECTED ADVERSE REACTIONS, contact Chartwell RX, LLC., at 845-232-1683 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
What interactions are listed?
Diuretics: Possibility of excessive hypotension ( 7.1). Lithium: Use with caution ( 7.4). Gold: Nitritoid reactions have been reported ( 7.5). NSAIDS use may lead to increased risk of renal impairment and loss of antihypertensive effect ( 7.6). mTOR inhibitor or neprilysin inhibitor use may increase angioedema risk ( 7.7)
Where can I find the official prescribing information?
Review the full prescribing information on DailyMed: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b7e49f05-6d4f-465a-b0d7-f704466a2e52
⚠️ Disclaimer
This summary is for educational purposes only and is not medical advice. Always consult your doctor, pharmacist, or other licensed healthcare professional before starting, stopping, or changing any medicine. Read full medical disclaimer.