Tizanidine Apo T2 60505 2648 07 Medication Summary
No separate FDA Medication Guide was found for this label. This summary is based on FDA/DailyMed prescribing information.
What is this medication?
This medication is described in FDA/DailyMed prescribing information. No separate FDA Medication Guide was found for this label. This summary is based on FDA/DailyMed prescribing information.
What is this medication used for?
Tizanidine capsules are indicated for the treatment of spasticity in adults.
What should I know before taking it?
Tizanidine capsules are contraindicated in patients: • taking strong CYP1A2 inhibitors [see Drug Interactions (7.1)]. • with a history of hypersensitivity to tizanidine or the ingredients in tizanidine capsules. Symptoms have included anaphylaxis and angioedema [see Warnings and Precautions (5.5)].
What important warnings are listed?
Hypotension: monitor for signs and symptoms of hypotension, in particular in patients receiving concurrent antihypertensives; tizanidine should not be used with other α2-adrenergic agonists (5.1, 7.7) • Risk of liver injury: monitor ALTs; discontinue tizanidine if liver injury occurs (5.2) • Sedation: Tizanidine may interfere with everyday activities; sedative effects of tizanidine, alcohol, and other central nervous system (CNS) depressants are additive (5.3, 7.4) • Hallucinations: consider discontinuation of tizanidine (5.4)
How is this medication usually taken?
Capsules: 2 mg, 4 mg and 6 mg
What side effects are listed?
The following clinically significant adverse reactions are described elsewhere in other sections of the prescribing information: • Hypotension [see Warnings and Precautions (5.1)] • Liver Injury [see Warnings and Precautions (5.2)] • Sedation [see Warnings and Precautions (5.3)] • Hallucinosis/Psychotic-Like Symptoms [see Warnings and Precautions (5.4)] • Hypersensitivity Reactions [see Warnings and Precautions (5.5)] • Withdrawal Adverse Reactions [see Warnings and Precautions (5.6)]
What interactions are listed?
Moderate or weak CYP1A2 inhibitors: avoid concomitant use; may cause hypotension, bradycardia, or excessive drowsiness; if concomitant use is necessary and adverse reactions occur, reduce tizanidine dosage or discontinue. (7.2, 12.3)
Where can I find the official prescribing information?
Review the full prescribing information on DailyMed: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3288d98d-aa49-4a36-a6d9-703645d8bcd7
⚠️ Disclaimer
This summary is for educational purposes only and is not medical advice. Always consult your doctor, pharmacist, or other licensed healthcare professional before starting, stopping, or changing any medicine. Read full medical disclaimer.